Prediction of scaffold proteins based on protein interaction and domain architectures
نویسندگان
چکیده
منابع مشابه
Prediction Accuracy Evaluation of Domain and Domain Combination Based Prediction Methods for Protein-Protein Interaction
Since the proposal of domain based protein-protein interaction prediction method by [3], there are many attempts to improve domain based protein-protein interaction prediction methods [1]. Among them, domain combination based protein-protein interaction method by [2] is quite appealing in the sense that it achieves very impressive prediction accuracy in some situations. However there is no conc...
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Most of a cell’s functional processes involve interactions among proteins, and a key challenge in proteomics is to better understand these complex interaction graphs at a systems level. Because of their importance in development and disease, protein-protein interactions (PPIs) have been the subject of intense research in recent years. In addition, a greater understanding of PPIs can be achieved...
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Protein interactions are of biological interest because they orchestrate a number of cellular processes such as metabolic pathways and immunological recognition. Recently, methods for predicting protein interactions using domain information are proposed and preliminary results have demonstrated their feasibility. In this paper, we develop two domain-based statistical models (neural networks and...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2016
ISSN: 1471-2105
DOI: 10.1186/s12859-016-1079-5